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frontend not working after update to 2.4.6

I have a development website that consists in a migration from 2.45 to 2.4.6. I upgraded all modules to latest version and my backend is working perfectly. However, frontend gives blank page and I get a 524 error from cloudflare.
I tried to use Luma or even Blank theme, same result.
As I have full access to the server, do you have any ideas or clues ?
I tried to set up debugging, but nothing seems to happen :/
TIA for your help